Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation
نویسندگان
چکیده
منابع مشابه
Inflammation-induced loss of Pdcd4 is mediated by phosphorylation-dependent degradation.
The tumor suppressor programmed cell death 4 (Pdcd4) is lost in various tumor tissues. Loss of Pdcd4 has been associated with increased tumorigenic potential and tumor progression. While various mechanisms of Pdcd4 regulation have been described, the effect of an inflammatory tumor microenvironment on Pdcd4 protein expression has not been characterized so far. In the present study, we aimed to ...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2011
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgr131